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Alloimmunization and genotype-predicted Rh antigen expression among chronically transfused patients with thalassemia receiving prophylactic C, E, and K matched red cells. (A) Antibody specificities detected among 40 chronically transfused patients with thalassemia. Columns for each specificity indicate patients’ corresponding antigen status (positive or negative) as reported by standard serologic typing methods. RHD and <t>RHCE</t> genotype-predicted Rh antigen expression among 5 Black (B) and 35 non-Black (C) patients with thalassemia. Partial antigens predicted from genotypes associated with alleles that result in Rh epitope(s) missing and absence of conventional antigen. RHD*DAU0 or RHCE*ce48C has not been shown to encode Rh proteins lacking epitopes and is considered altered antigens.
Rhce Beadchip Arrays, supplied by Bioarray Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Alloimmunization and genotype-predicted Rh antigen expression among chronically transfused patients with thalassemia receiving prophylactic C, E, and K matched red cells. (A) Antibody specificities detected among 40 chronically transfused patients with thalassemia. Columns for each specificity indicate patients’ corresponding antigen status (positive or negative) as reported by standard serologic typing methods. RHD and RHCE genotype-predicted Rh antigen expression among 5 Black (B) and 35 non-Black (C) patients with thalassemia. Partial antigens predicted from genotypes associated with alleles that result in Rh epitope(s) missing and absence of conventional antigen. RHD*DAU0 or RHCE*ce48C has not been shown to encode Rh proteins lacking epitopes and is considered altered antigens.

Journal: Blood Advances

Article Title: Rh alloimmunization in chronically transfused patients with thalassemia receiving RhD, C, E, and K matched transfusions

doi: 10.1182/bloodadvances.2020003732

Figure Lengend Snippet: Alloimmunization and genotype-predicted Rh antigen expression among chronically transfused patients with thalassemia receiving prophylactic C, E, and K matched red cells. (A) Antibody specificities detected among 40 chronically transfused patients with thalassemia. Columns for each specificity indicate patients’ corresponding antigen status (positive or negative) as reported by standard serologic typing methods. RHD and RHCE genotype-predicted Rh antigen expression among 5 Black (B) and 35 non-Black (C) patients with thalassemia. Partial antigens predicted from genotypes associated with alleles that result in Rh epitope(s) missing and absence of conventional antigen. RHD*DAU0 or RHCE*ce48C has not been shown to encode Rh proteins lacking epitopes and is considered altered antigens.

Article Snippet: RH genotyping was performed with RHD and RHCE BeadChip arrays (Bioarray/Immucor), and polymerase chain reaction–based assays, as described previously.

Techniques: Expressing

RHD and  RHCE  alleles among 40 chronically transfused patients with thalassemia

Journal: Blood Advances

Article Title: Rh alloimmunization in chronically transfused patients with thalassemia receiving RhD, C, E, and K matched transfusions

doi: 10.1182/bloodadvances.2020003732

Figure Lengend Snippet: RHD and RHCE alleles among 40 chronically transfused patients with thalassemia

Article Snippet: RH genotyping was performed with RHD and RHCE BeadChip arrays (Bioarray/Immucor), and polymerase chain reaction–based assays, as described previously.

Techniques:

Alloimmunization and genotype-predicted Rh antigen expression among chronically transfused patients with SCD receiving prophylactic C, E, and K matched red cells by simple transfusion. (A) Antibody specificities detected among 48 chronically transfused patients with SCD. Columns for each specificity indicate patients’ corresponding antigen status (positive or negative) as reported by standard serologic or genotyping methods. (B) RHD and RHCE genotype-predicted Rh antigen expression among patients with SCD. Partial antigens predicted from genotypes with variant alleles that result in Rh epitope(s) missing and absence of conventional antigen. RHD*DAU0 or RHCE*ce48C has not been shown to encode Rh proteins lacking epitopes and is considered altered antigens.

Journal: Blood Advances

Article Title: Rh alloimmunization in chronically transfused patients with thalassemia receiving RhD, C, E, and K matched transfusions

doi: 10.1182/bloodadvances.2020003732

Figure Lengend Snippet: Alloimmunization and genotype-predicted Rh antigen expression among chronically transfused patients with SCD receiving prophylactic C, E, and K matched red cells by simple transfusion. (A) Antibody specificities detected among 48 chronically transfused patients with SCD. Columns for each specificity indicate patients’ corresponding antigen status (positive or negative) as reported by standard serologic or genotyping methods. (B) RHD and RHCE genotype-predicted Rh antigen expression among patients with SCD. Partial antigens predicted from genotypes with variant alleles that result in Rh epitope(s) missing and absence of conventional antigen. RHD*DAU0 or RHCE*ce48C has not been shown to encode Rh proteins lacking epitopes and is considered altered antigens.

Article Snippet: RH genotyping was performed with RHD and RHCE BeadChip arrays (Bioarray/Immucor), and polymerase chain reaction–based assays, as described previously.

Techniques: Expressing, Variant Assay